Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
W5NT23_SHEEPPeptidylprolyl isomerase. (140 aa)    
Predicted Functional Partners:
SSR4
Signal sequence receptor subunit 4.
   
 
 0.494
NENF
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
   
  
 0.469
PPIB
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.464
FOXRED2
FAD dependent oxidoreductase domain containing 2.
    
 
 0.463
SUMF2
FGE-sulfatase domain-containing protein.
    
 
 0.461
PCYOX1
Prenylcysteine oxidase 1.
      
 0.459
POGLUT1
Protein O-glucosyltransferase 1.
   
  
 0.458
LARP1
La ribonucleoprotein domain family member 1.
   
 
 0.442
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.429
SSR2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
   
 
 0.426
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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