STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NT24_SHEEPUncharacterized protein. (4129 aa)    
Predicted Functional Partners:
LAMA4
Laminin subunit alpha 4.
     
 0.657
MYOC
Myocilin.
   
  
 0.625
MFAP5
Microfibril associated protein 5.
   
 
 0.615
VARS
GST C-terminal domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.598
HLA-DRA
Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.
    
 
 0.577
SUCLA2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
      
 0.567
W5PRD9_SHEEP
Anticodon_1 domain-containing protein.
      
 0.567
PRDM5
Zinc finger protein.
    
 
 0.562
ERC1
ELKS/RAB6-interacting/CAST family member 1.
      
 0.561
BCAN
Brevican.
    
  0.541
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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