STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NT27_SHEEPPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (200 aa)    
Predicted Functional Partners:
ELANE
Elastase, neutrophil expressed; Belongs to the peptidase S1 family.
  
0.651
AGT
Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.
   
 0.591
LOC101116249
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
0.568
LOC114112429
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
0.563
W5P9F4_SHEEP
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
0.560
LOC101117013
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.532
PRSS27
Serine protease 27; Belongs to the peptidase S1 family.
  
     0.531
PRTN3
Proteinase 3; Belongs to the peptidase S1 family.
  
0.530
CD4
T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
   
 0.527
MMP9
Matrix metallopeptidase 9.
   
 0.492
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.