STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NT28_SHEEPSSD domain-containing protein. (1183 aa)    
Predicted Functional Partners:
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.958
SHH
Uncharacterized protein.
   
 0.946
ENSOARP00000001737
annotation not available
   
 0.896
DHH
Uncharacterized protein.
   
 0.895
IHH
Indian hedgehog signaling molecule.
   
 0.883
GLI1
GLI family zinc finger 1.
   
 0.809
GLI2
GLI family zinc finger 2.
   
 0.791
GLI3
GLI family zinc finger 3.
   
 0.760
SUFU
SUFU negative regulator of hedgehog signaling.
    
 
 0.750
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.719
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.