STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENTPD8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (382 aa)    
Predicted Functional Partners:
ABHD12B
Abhydrolase domain containing 12B.
      
 0.871
DEPDC7
DEP domain containing 7.
   
  
 0.815
RASL10B
RAS like family 10 member B.
   
  
 0.804
KRT23
Keratin 23; Belongs to the intermediate filament family.
      
 0.800
RASL11B
RAS like family 11 member B.
   
  
 0.791
TMEM47
Transmembrane protein 47.
      
 0.789
SORBS2
Uncharacterized protein.
   
  
 0.659
SELP
P-selectin; Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.
   
  
 0.546
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels.
      
 0.538
W5NUV0_SHEEP
Uncharacterized protein.
      
 0.538
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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