Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TAS2R60Taste receptor type 2. (318 aa)    
Predicted Functional Partners:
TAS1R2
Taste 1 receptor member 2.
     
 0.649
LOC101102056
Taste receptor type 2.
   
  
 0.647
TAS1R1
Taste 1 receptor member 1.
     
 0.624
TAS1R3
Taste 1 receptor member 3; Belongs to the G-protein coupled receptor 3 family.
     
 0.582
PKD1L3
Polycystin 1 like 3, transient receptor potential channel interacting.
      
 0.547
PKD1L2
Uncharacterized protein.
      
 0.547
LOC101121003
Taste receptor type 2.
     
 0.500
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
      
 0.491
CASR
Calcium sensing receptor.
     
 0.432
SMTNL1
Calponin-homology (CH) domain-containing protein.
      
 0.422
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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