STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101112427CAP18_C domain-containing protein. (175 aa)    
Predicted Functional Partners:
CATHL2
Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.
  
 
0.992
CATHL3
Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.
  
 
0.940
NFKB1
Nuclear factor kappa B subunit 1.
   
 
 0.912
RELA
RELA proto-oncogene, NF-kB subunit.
   
 
 0.903
W5P1Y8_SHEEP
Uncharacterized protein.
   
 
  0.680
HMGB2
Uncharacterized protein.
      
 0.667
LCN2
Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.597
S100A8
S100 calcium binding protein A8; Belongs to the S-100 family.
   
 
 0.590
MXRA8
Matrix remodeling associated 8.
      
 0.535
W5P1P8_SHEEP
Uncharacterized protein.
      
 0.535
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (28%) [HD]