Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPN20Protein tyrosine phosphatase non-receptor type 20. (445 aa)    
Predicted Functional Partners:
FAM72A
Uncharacterized protein.
      
 0.852
FRMPD2
FERM and PDZ domain containing 2.
 
   
 0.835
ARHGEF5
Rho guanine nucleotide exchange factor 5.
   
  
 0.831
ARHGAP11A
Rho GTPase activating protein 11A.
      
 0.821
BOLA2B
Uncharacterized protein; Belongs to the BolA/IbaG family.
      
 0.675
TRPM8
Transient receptor potential cation channel subfamily M member 8.
   
 
 0.659
PTPN23
ALIX_LYPXL_bnd domain-containing protein.
    
 0.656
SCGB1C1
Uncharacterized protein.
      
 0.580
GTF2I
Uncharacterized protein.
      
 0.576
W5Q9Y6_SHEEP
Peptidase M60 domain-containing protein.
      
 0.568
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.