STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MDM1Mdm1 nuclear protein. (724 aa)    
Predicted Functional Partners:
ZNF232
SCAN box domain-containing protein.
      
 0.767
NEURL4
Uncharacterized protein.
      
 0.686
CAND1
Cullin associated and neddylation dissociated 1.
      
 0.627
OLIG3
Oligodendrocyte transcription factor 3.
      
 0.621
ELP5
Elongator acetyltransferase complex subunit 5.
      
 0.604
ZNF23-2
Uncharacterized protein.
      
 0.584
IL22RA1
Interleukin 22 receptor subunit alpha 1.
      
 0.571
NOL4
Nucleolar protein 4.
      
 0.562
FAM118A
Family with sequence similarity 118 member A.
      
 0.554
CDK5R2
Cyclin dependent kinase 5 regulatory subunit 2.
      
 0.552
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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