STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CST6Cystatin E/M; Belongs to the cystatin family. (149 aa)    
Predicted Functional Partners:
LGMN
Legumain.
    
 
 0.954
CYP4X1
Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family.
   
 
 0.787
CTSC
Cathepsin C; Belongs to the peptidase C1 family.
   
 0.632
RANGAP1
Ran GTPase activating protein 1.
   
 
 0.620
AVEN
Uncharacterized protein.
    
 0.620
PRSS35
Serine protease 35.
      
 0.619
KRT2.11
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
 
 0.593
PRR9
Proline rich 9.
      
 0.589
AURKC
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.579
W5PWR4_SHEEP
Protein kinase domain-containing protein.
   
 0.579
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.