STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NTC1_SHEEPBZIP domain-containing protein. (163 aa)    
Predicted Functional Partners:
NFE2L1
Nuclear factor, erythroid 2 like 1.
   
 0.491
NFE2L3
Nuclear factor, erythroid 2 like 3.
   
 0.491
BACH2
BTB domain and CNC homolog 2.
   
 0.491
BACH1
BTB domain and CNC homolog 1.
   
 0.491
NFE2
Nuclear factor, erythroid 2.
   
 0.491
NFE2L2
Nuclear factor, erythroid 2 like 2.
   
 0.491
FOS
Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...]
    
 
 0.485
FOSL2
FOS like 2, AP-1 transcription factor subunit.
    
 
 0.485
MAFA
Uncharacterized protein.
 
     0.444
JUN
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.411
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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