Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5NTD5_SHEEPDHR-2 domain-containing protein; Belongs to the DOCK family. (141 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.834
DOCK10
Dedicator of cytokinesis 10; Belongs to the DOCK family.
   
 0.596
W5P784_SHEEP
Uncharacterized protein.
   
 0.583
RHOJ
Ras homolog family member J.
   
 0.567
RAC1
Uncharacterized protein.
   
 0.565
RAC3
Rac family small GTPase 3.
   
 0.565
RHOU
Ras homolog family member U.
   
 0.531
RHOV
Uncharacterized protein.
   
 0.522
RHOQ
Ras homolog family member Q.
   
 0.516
RHOH
RhoH.
   
 0.493
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (22%) [HD]