Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
GPR37G protein-coupled receptor 37. (604 aa)    
Predicted Functional Partners:
PRKN
Ubiquitin-like domain-containing protein.
    
 0.988
PSAP
Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
     
 0.988
W5P3W8_SHEEP
RBR-type E3 ubiquitin transferase.
    
 
 0.823
FAM219A
Family with sequence similarity 219 member A.
    
   0.803
SYVN1
Synoviolin 1.
    
 
 0.782
LGI1
Leucine rich glioma inactivated 1.
   
  
 0.707
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
   
  
 0.702
GPR158
G protein-coupled receptor 158.
   
  
 0.700
LUM
Lumican.
      
 0.699
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain.
      
 0.699
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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