Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (480 aa)    
Predicted Functional Partners:
EIF2B2
Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
 0.999
EIF2B1
Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
 0.999
EIF2B4
Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family.
   
 0.999
EIF2B5
Eukaryotic translation initiation factor 2B subunit epsilon.
   
0.999
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
   
 0.961
EIF2S3
Tr-type G domain-containing protein.
   
 0.950
EIF2S2
Eukaryotic translation initiation factor 2 subunit beta.
   
 0.949
RSL24D1
Ribosomal L24 domain containing 1.
   
  
 0.856
EIF1AD
Eukaryotic translation initiation factor 1A domain containing.
   
  
 0.852
PPP1R15B
Protein phosphatase 1 regulatory subunit 15B.
    
 
 0.773
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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