STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EXD3Exonuclease 3'-5' domain containing 3. (861 aa)    
Predicted Functional Partners:
DBF4B
DBF4 zinc finger B.
    
 
 0.703
RNF175
Ring finger protein 175.
      
 0.694
CPO
Carboxypeptidase O.
   
 
 0.620
EXD1
Exonuclease 3'-5' domain containing 1.
      
 0.614
PAX8
Paired box 8.
      
 0.581
NUDCD1
NudC domain containing 1.
    
 
 0.552
EFCAB6
EF-hand calcium binding domain 6.
    
 0.535
PNLDC1
PARN like, ribonuclease domain containing 1.
      
 0.532
PTAR1
Protein prenyltransferase alpha subunit repeat containing 1.
      
 0.512
FBXW12
WD_REPEATS_REGION domain-containing protein.
    
 
 0.485
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.