Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
FRMPD2FERM and PDZ domain containing 2. (1296 aa)    
Predicted Functional Partners:
REM1
Uncharacterized protein.
    
 0.944
SNTA1
Syntrophin alpha 1.
      
 0.905
PTPN20
Protein tyrosine phosphatase non-receptor type 20.
 
   
 0.835
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
    
 0.715
FRMPD1
FERM and PDZ domain containing 1.
      
 0.696
GPSM1
G protein signaling modulator 1.
    
 
 0.662
SARS1
Seryl-tRNA synthetase.
    
   0.631
ARL3
ADP-ribosylation factor-like 3; Belongs to the small GTPase superfamily. Arf family.
   
 0.605
PKN2
Protein kinase N2.
    
   0.577
GPSM2
G protein signaling modulator 2.
    
 
 0.572
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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