STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCHS2Dachsous cadherin-related 2. (2813 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.616
JUP
Junction plakoglobin.
    
 0.616
ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2.
   
  
 0.542
MOB2
Uncharacterized protein.
   
  
 0.540
FAT2
FAT atypical cadherin 2.
   
0.517
CDHR5
Cadherin related family member 5.
   
0.508
PCDH15
Protocadherin related 15.
   
0.508
FAT3
FAT atypical cadherin 3.
   
0.491
W5P257_SHEEP
WD_REPEATS_REGION domain-containing protein.
      
 0.480
FAT1
FAT atypical cadherin 1.
   
0.471
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.