Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DCHS2Dachsous cadherin-related 2. (2813 aa)    
Predicted Functional Partners:
DCHS1
Dachsous cadherin-related 1.
     
0.914
FAT4
FAT atypical cadherin 4.
   
0.843
CTNNA1
Catenin alpha 1.
    
 0.727
CTNNA2-2
Uncharacterized protein.
    
 0.727
CTNNA2
Catenin alpha 2.
    
 0.727
W5QIC9_SHEEP
Uncharacterized protein.
    
 0.727
FAT3
FAT atypical cadherin 3.
   
0.720
CDH12
Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.
    
0.714
CDH13
Cadherin 13.
   
 
0.657
CDH18
Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins.
   
 
 
0.653
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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