STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TPX2TPX2 microtubule nucleation factor. (747 aa)    
Predicted Functional Partners:
AURKA
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.952
COG3
Component of oligomeric golgi complex 3.
    
 0.880
COG5
Component of oligomeric golgi complex 5.
   
 0.879
COG2
Component of oligomeric golgi complex 2.
    
 0.877
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 0.877
COG1
Component of oligomeric golgi complex 1.
    
 0.873
COG8
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
   
 0.853
NUSAP1
Uncharacterized protein.
   
  
 0.780
COG4
Component of oligomeric golgi complex 4.
    
 0.764
SMIM7
Small integral membrane protein 7.
    
 0.764
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.