STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECTD3HECT domain E3 ubiquitin protein ligase 3. (821 aa)    
Predicted Functional Partners:
PGM2
Phosphoglucomutase 2; Belongs to the phosphohexose mutase family.
   
    0.780
TRIP12
Thyroid hormone receptor interactor 12.
   
 
0.711
KIAA2013
KIAA2013.
      
 0.677
DHRS7
Dehydrogenase/reductase 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.621
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.606
GGT7
Gamma-glutamyltransferase 7.
      
 0.578
PLS1
Plastin 1.
    
 
 0.542
RNF220
RING-type domain-containing protein.
    
 
 0.523
CHD2
Uncharacterized protein.
   
 
 0.508
MTDH
Metadherin.
    
 
 0.505
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.