STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NTM3_SHEEPUncharacterized protein. (649 aa)    
Predicted Functional Partners:
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
   
  0.902
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
  0.902
NTNG1
Netrin G1.
    
 0.582
NTN1
Netrin 1.
    
 0.556
NTNG2
Netrin G2.
    
 0.556
NTN5
Netrin 5.
    
 0.556
NTN3
Netrin 3.
    
 0.556
USHBP1
USH1 protein network component harmonin binding protein 1.
    
 0.527
PPP1R3C
Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
      
 0.524
TRIT1
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.
   
  
 0.515
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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