STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLX1Distal-less homeobox 1. (257 aa)    
Predicted Functional Partners:
LHX6
LIM homeobox 6.
   
  
 0.894
ASCL1
Achaete-scute family bHLH transcription factor 1.
   
  
 0.833
NEUROG2
BHLH domain-containing protein.
   
  
 0.741
W5P6Z2_SHEEP
Homeobox domain-containing protein.
   
 
 0.714
ATOH7
Atonal bHLH transcription factor 7.
   
  
 0.712
DLX2
Distal-less homeobox 2.
   
 
0.693
SST
Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin.
      
 0.649
LHX8
LIM homeobox 8.
   
  
 0.624
NPAS1
Neuronal PAS domain protein 1.
      
 0.601
CUX2
Homeobox protein cut-like.
   
  
 0.593
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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