DELE1 protein (Ovis aries) - STRING interaction network

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

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Score

DELE1

DAP3 binding cell death enhancer 1. (520 aa)

Predicted Functional Partners:

ERLEC1

0.716

OS9

0.716

DERL1

0.691

DERL2

0.687

OAZ1

0.654

TK2

0.626

INTS2

0.626

DGUOK

0.613

W5QBF3_SHEEP

0.613

EIF2A

0.611

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DELE1	DERL1	ENSOARP00000001523	ENSOARP00000011741	DAP3 binding cell death enhancer 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.691
DELE1	DERL2	ENSOARP00000001523	ENSOARP00000003322	DAP3 binding cell death enhancer 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.687
DELE1	DGUOK	ENSOARP00000001523	ENSOARP00000013053	DAP3 binding cell death enhancer 1.	Deoxyguanosine kinase.	0.613
DELE1	EIF2A	ENSOARP00000001523	ENSOARP00000004828	DAP3 binding cell death enhancer 1.	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	0.611
DELE1	ERLEC1	ENSOARP00000001523	ENSOARP00000004276	DAP3 binding cell death enhancer 1.	Endoplasmic reticulum lectin 1.	0.716
DELE1	INTS2	ENSOARP00000001523	ENSOARP00000016668	DAP3 binding cell death enhancer 1.	Integrator complex subunit 2.	0.626
DELE1	OAZ1	ENSOARP00000001523	ENSOARP00000015111	DAP3 binding cell death enhancer 1.	Ornithine decarboxylase antizyme 1.	0.654
DELE1	OS9	ENSOARP00000001523	ENSOARP00000005994	DAP3 binding cell death enhancer 1.	OS9 endoplasmic reticulum lectin.	0.716
DELE1	TK2	ENSOARP00000001523	ENSOARP00000002023	DAP3 binding cell death enhancer 1.	Thymidine kinase 2.	0.626
DELE1	W5QBF3_SHEEP	ENSOARP00000001523	ENSOARP00000020050	DAP3 binding cell death enhancer 1.	Uncharacterized protein.	0.613
DERL1	DELE1	ENSOARP00000011741	ENSOARP00000001523	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	DAP3 binding cell death enhancer 1.	0.691
DERL1	DERL2	ENSOARP00000011741	ENSOARP00000003322	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.994
DERL1	ERLEC1	ENSOARP00000011741	ENSOARP00000004276	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.938
DERL1	OS9	ENSOARP00000011741	ENSOARP00000005994	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.973
DERL2	DELE1	ENSOARP00000003322	ENSOARP00000001523	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	DAP3 binding cell death enhancer 1.	0.687
DERL2	DERL1	ENSOARP00000003322	ENSOARP00000011741	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.994
DERL2	ERLEC1	ENSOARP00000003322	ENSOARP00000004276	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.929
DERL2	OS9	ENSOARP00000003322	ENSOARP00000005994	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.980
DGUOK	DELE1	ENSOARP00000013053	ENSOARP00000001523	Deoxyguanosine kinase.	DAP3 binding cell death enhancer 1.	0.613
EIF2A	DELE1	ENSOARP00000004828	ENSOARP00000001523	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	DAP3 binding cell death enhancer 1.	0.611