STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
URODUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (367 aa)    
Predicted Functional Partners:
UROS
Uroporphyrinogen III synthase.
  
 
 0.997
CPOX
Uncharacterized protein.
  
 0.997
PPOX
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.989
HMBS
Hydroxymethylbilane synthase.
 0.975
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
  
 0.956
ALAD
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.920
W5Q2F3_SHEEP
Uncharacterized protein.
  
 
 0.898
LOC101111335
Flavodoxin-like domain-containing protein.
    
 0.827
MOCS1
Molybdenum cofactor synthesis 1.
    
  0.808
SLCO4C1
Solute carrier organic anion transporter family member.
      
 0.763
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (34%) [HD]