STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LETM2Leucine zipper and EF-hand containing transmembrane protein 2. (491 aa)    
Predicted Functional Partners:
FAM118A
Family with sequence similarity 118 member A.
    
 
 0.774
RHBDD3
Rhomboid domain containing 3.
      
 0.769
TMEM39B
Transmembrane protein 39B.
      
 0.750
DNAJC18
DnaJ heat shock protein family (Hsp40) member C18.
   
 
 0.731
REEP6
Receptor expression-enhancing protein.
      
 0.693
BRF2
BRF2 RNA polymerase III transcription initiation factor subunit.
      
 0.682
GPAT2
Glycerol-3-phosphate acyltransferase 2, mitochondrial.
      
 0.621
PLD6
Phospholipase D family member 6.
      
 0.619
GOT1L1
Glutamic-oxaloacetic transaminase 1 like 1.
    
 
 0.615
EIF4EBP1
Eukaryotic translation initiation factor 4E binding protein 1.
      
 0.613
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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