STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GATAD2BGATA zinc finger domain containing 2B. (592 aa)    
Predicted Functional Partners:
GATAD2A
GATA zinc finger domain containing 2A.
   
0.996
CHD4
Uncharacterized protein.
   
 0.988
CHD3
Chromodomain helicase DNA binding protein 3.
   
 0.988
MTA2
Metastasis associated 1 family member 2.
   
 0.987
W5NT16_SHEEP
Uncharacterized protein.
   
 0.985
CHD5
Chromodomain helicase DNA binding protein 5.
   
 0.981
W5P8P1_SHEEP
Uncharacterized protein.
   
 0.957
MTA3
Uncharacterized protein.
   
 0.957
CDK2AP1
Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family.
    
 
 0.951
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.946
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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