STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP4Rho GTPase activating protein 4. (1051 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
0.843
WAS
WASP actin nucleation promoting factor.
   
 0.759
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
      
 0.710
CORO1A
Coronin; Belongs to the WD repeat coronin family.
   
  
 0.688
GAS7
Growth arrest specific 7.
   
 0.688
ITSN1
Intersectin 1.
   
 0.688
YIPF6
Protein YIPF.
      
 0.688
CAPN13
Calpain 13; Belongs to the peptidase C2 family.
      
 0.688
ZSCAN12
Zinc finger and SCAN domain containing 12.
      
 0.613
WASL
WASP like actin nucleation promoting factor.
   
 0.601
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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