TRAF2 protein (Ovis aries) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

TRAF2

TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (532 aa)

Predicted Functional Partners:

TRADD

0.986

RIPK1

0.960

BIRC3

0.927

FADD

0.889

BIRC2

0.888

USP48

0.882

TBK1

0.856

MIB2

0.836

TRAF1

0.822

TANK

0.822

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIRC2	BIRC3	ENSOARP00000006949	ENSOARP00000006810	Baculoviral IAP repeat containing 2.	Baculoviral IAP repeat containing 3.	0.911
BIRC2	FADD	ENSOARP00000006949	ENSOARP00000019828	Baculoviral IAP repeat containing 2.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.954
BIRC2	RIPK1	ENSOARP00000006949	ENSOARP00000001620	Baculoviral IAP repeat containing 2.	Receptor interacting serine/threonine kinase 1.	0.813
BIRC2	TBK1	ENSOARP00000006949	ENSOARP00000003587	Baculoviral IAP repeat containing 2.	TANK binding kinase 1.	0.569
BIRC2	TRADD	ENSOARP00000006949	ENSOARP00000002885	Baculoviral IAP repeat containing 2.	TNFRSF1A associated via death domain.	0.897
BIRC2	TRAF1	ENSOARP00000006949	ENSOARP00000006024	Baculoviral IAP repeat containing 2.	TNF receptor-associated factor.	0.779
BIRC2	TRAF2	ENSOARP00000006949	ENSOARP00000001587	Baculoviral IAP repeat containing 2.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.888
BIRC3	BIRC2	ENSOARP00000006810	ENSOARP00000006949	Baculoviral IAP repeat containing 3.	Baculoviral IAP repeat containing 2.	0.911
BIRC3	FADD	ENSOARP00000006810	ENSOARP00000019828	Baculoviral IAP repeat containing 3.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.945
BIRC3	RIPK1	ENSOARP00000006810	ENSOARP00000001620	Baculoviral IAP repeat containing 3.	Receptor interacting serine/threonine kinase 1.	0.831
BIRC3	TBK1	ENSOARP00000006810	ENSOARP00000003587	Baculoviral IAP repeat containing 3.	TANK binding kinase 1.	0.569
BIRC3	TRADD	ENSOARP00000006810	ENSOARP00000002885	Baculoviral IAP repeat containing 3.	TNFRSF1A associated via death domain.	0.876
BIRC3	TRAF1	ENSOARP00000006810	ENSOARP00000006024	Baculoviral IAP repeat containing 3.	TNF receptor-associated factor.	0.888
BIRC3	TRAF2	ENSOARP00000006810	ENSOARP00000001587	Baculoviral IAP repeat containing 3.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.927
FADD	BIRC2	ENSOARP00000019828	ENSOARP00000006949	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Baculoviral IAP repeat containing 2.	0.954
FADD	BIRC3	ENSOARP00000019828	ENSOARP00000006810	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Baculoviral IAP repeat containing 3.	0.945
FADD	MIB2	ENSOARP00000019828	ENSOARP00000003014	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Mindbomb E3 ubiquitin protein ligase 2.	0.545
FADD	RIPK1	ENSOARP00000019828	ENSOARP00000001620	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Receptor interacting serine/threonine kinase 1.	0.998
FADD	TANK	ENSOARP00000019828	ENSOARP00000007272	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	TRAF family member associated NFKB activator.	0.531
FADD	TBK1	ENSOARP00000019828	ENSOARP00000003587	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	TANK binding kinase 1.	0.575