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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM8Tripartite motif containing 8. (480 aa)    
Predicted Functional Partners:
TRIM66
Tripartite motif containing 66.
      
 0.898
TRIM3
Tripartite motif containing 3.
    
 
 0.803
TRIM44
Tripartite motif containing 44.
    
 
 0.785
TRIM32
Tripartite motif containing 32.
      
 0.781
TRIM62
Tripartite motif containing 62.
      
 0.723
MFSD13A
Major facilitator superfamily domain containing 13A.
      
 0.659
ZMIZ2
Zinc finger MIZ-type containing 2.
   
 0.627
FAM110B
FAM110_C domain-containing protein.
      
 0.620
WDR75
WD repeat domain 75.
      
 0.605
CUEDC2
CUE domain containing 2.
      
 0.601
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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