Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDF1Endothelial differentiation related factor 1. (148 aa)    
Predicted Functional Partners:
RPS3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.869
RPS21
40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.
   
 
 0.848
RPL29
60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family.
   
 
 0.847
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
   0.846
RPS5
Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.
   
   0.829
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
   
    0.826
GNB2L1
Guanine nucleotide-binding protein beta polypeptide 2-like 1.
   
 
 0.820
W5PR06_SHEEP
WD_REPEATS_REGION domain-containing protein.
   
 
 0.820
RPL8
Ribosomal protein L8.
   
   0.812
RPL32
Ribosomal protein L32.
   
 
 0.799
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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