Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
W5NTV9_SHEEPGB1/RHD3-type G domain-containing protein. (481 aa)    
Predicted Functional Partners:
PLAC8
Placenta associated 8.
   
    0.589
W5Q1E8_SHEEP
Uncharacterized protein.
   
    0.582
LOC101119773
GB1/RHD3-type G domain-containing protein.
  
   
0.556
GBP5
Guanylate binding protein 5.
  
 
 
0.518
W5Q0D7_SHEEP
GB1/RHD3-type G domain-containing protein.
   
 
  0.433
W5NU19_SHEEP
GBP_C domain-containing protein.
   
 
  0.423
SFN
14-3-3 protein sigma; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53 (By similarity).
    
  0.419
LOC101117013
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 
 0.416
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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