Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
W5NTY4_SHEEPUncharacterized protein. (559 aa)    
Predicted Functional Partners:
CYLC2
Cylicin_N domain-containing protein.
  
 0.775
CCIN
Calicin.
   
 0.762
LOC101115856
Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.
   
 
 0.670
RIBC1
RIB43A domain with coiled-coils 1.
   
 
 0.669
PIH1D3
PIH1 domain containing 3.
      
 0.598
RNF114
Ring finger protein 114.
      
 0.579
DYNLT3
Dynein light chain Tctex-type 3; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity).
    
 
 0.577
W5NSU2_SHEEP
Uncharacterized protein.
      
 0.552
APOOL
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
  
 0.534
AFF2
AF4/FMR2 family member 2.
   
 0.529
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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