STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)    
Predicted Functional Partners:
SDR16C5
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.972
RDH10
Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.965
ALDH1A1
Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.
   
 
 0.962
DHRS3
Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.962
ALDH1A2
Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.
   
 
 0.961
ALDH1A3
Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.
   
 
 0.954
RDH12
Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.952
ADH5
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 
 0.951
LRAT
LRAT domain-containing protein.
   
 
 0.950
LOC101120535
Uncharacterized protein.
  
 0.947
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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