STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP22Rho GTPase activating protein 22. (705 aa)    
Predicted Functional Partners:
GOLGA7B
Golgin A7 family member B.
      
 0.846
MEAK7
MTOR associated protein, eak-7 homolog.
      
 0.833
EVI2A
Uncharacterized protein.
      
 0.821
SH2D5
SH2 domain containing 5.
      
 0.821
SPOCD1
SPOC domain containing 1.
      
 0.786
RAB25
RAB25, member RAS oncogene family.
    
 0.758
MXRA8
Matrix remodeling associated 8.
      
 0.747
DHX32
DEAH-box helicase 32 (putative).
      
 0.739
RGS19
Regulator of G protein signaling 19.
      
 0.723
AGFG1
ArfGAP with FG repeats 1.
      
 0.698
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.