STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOE1Target of EGR1, exonuclease. (538 aa)    
Predicted Functional Partners:
GEMIN8
Gem nuclear organelle associated protein 8.
      
 0.895
MUTYH
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
      
 0.866
GEMIN2
Gem nuclear organelle associated protein 2.
      
 0.865
SNX14
Sorting nexin 14.
      
 0.860
GEMIN4
Gem nuclear organelle associated protein 4.
   
  
 0.844
GEMIN5
Gem nuclear organelle associated protein 5.
      
 0.783
TESK2
Testis associated actin remodelling kinase 2.
    
 
 0.733
DCP2
Decapping mRNA 2.
     
 0.688
EGR1
DUF3446 domain-containing protein.
    
 
 0.653
DDX20
DEAD-box helicase 20.
   
 
 0.627
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.