Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAPOLGPoly(A) polymerase gamma. (817 aa)    
Predicted Functional Partners:
YTHDC1
YTH domain containing 1.
   
 0.957
PCF11
PCF11 cleavage and polyadenylation factor subunit.
    
 0.950
SYMPK
Symplekin.
   
 0.949
RBM26
RNA binding motif protein 26.
   
 
 0.944
YTHDC2
YTH domain containing 2.
   
 0.944
ZC3H3
Zinc finger CCCH-type containing 3.
    
 0.941
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.941
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
    
 0.937
RBBP6
RB binding protein 6, ubiquitin ligase.
   
 0.935
PAPOLA
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
  
  
0.934
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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