STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO43F-box protein 43. (707 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.984
W5P6X3_SHEEP
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 
 0.940
CDK1
Cell division cycle 2 protein isoform 1; Belongs to the protein kinase superfamily.
   
 0.925
CUL1
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.925
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.914
RBX1
Ring-box 1.
   
 
 0.912
FBXW11
F-box and WD repeat domain containing 11.
    
 0.911
PPP2R1B
Protein phosphatase 2 scaffold subunit Abeta.
   
 0.906
PPP2R1A
Protein phosphatase 2 scaffold subunit Aalpha.
   
 0.906
PPP2CB
Serine/threonine-protein phosphatase.
    
  0.902
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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