STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DENND4BDENN domain containing 4B. (1431 aa)    
Predicted Functional Partners:
DENND1C
DENN domain containing 1C.
    
 
 0.899
RAB10
Uncharacterized protein.
    
 0.810
RAB8B
RAB8B, member RAS oncogene family.
    
 0.778
AVL9
AVL9 cell migration associated.
      
 0.720
DENND1A
UDENN domain-containing protein.
   
 
 0.720
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
      
 0.681
DENND5A
DENN domain containing 5A.
    
 
0.662
DENND5B
DENN domain containing 5B.
    
 
0.649
TMEM160
Transmembrane protein 160.
      
 0.613
DENND3
DENN domain containing 3.
      
0.589
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.