STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NU27_SHEEPRho-GAP domain-containing protein. (148 aa)    
Predicted Functional Partners:
RHOBTB3
Rho related BTB domain containing 3.
   
 0.730
NUDT7
Nudix hydrolase 7.
   
    0.674
GTF2E2
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
      
 0.590
MAP3K9
Mitogen-activated protein kinase kinase kinase.
   
  
 0.581
RIOK1
Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
      
 0.580
RHOA
RHOA.
   
 0.540
W5Q4M2_SHEEP
Uncharacterized protein.
   
 0.540
RHOB
Uncharacterized protein.
   
 0.540
PIWIL2
Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.
      
 0.538
ARHGAP29
Rho GTPase activating protein 29.
   
 
 0.517
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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