STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSPBP1HSPA (Hsp70) binding protein 1. (348 aa)    
Predicted Functional Partners:
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.904
SEC61A1
SEC61 translocon alpha 1 subunit.
  
 
 0.823
RPL11
Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
  
 0.817
TSEN15
tRNA splicing endonuclease subunit 15.
      
 0.811
MRPL17
Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
  
 0.809
GTF2A2
Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.
   
  
 0.804
RPS18
Ribosomal protein S18; Belongs to the universal ribosomal protein uS13 family.
  
 
 0.803
RPS3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.803
MRPS9
Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.803
RPS11
Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.
  
 
 0.803
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.