STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105607776Uncharacterized protein. (190 aa)    
Predicted Functional Partners:
W5P1Y8_SHEEP
Uncharacterized protein.
  
 
 
0.703
HLA-DRA
Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.
   
   0.522
SC52_SHEEP
Cathelin-related peptide SC5; Broad spectrum bactericidal agent.
  
 
 
0.497
W5NUU0_SHEEP
Uncharacterized protein.
   
 
 
0.487
LCN2
Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.474
ELANE
Elastase, neutrophil expressed; Belongs to the peptidase S1 family.
   
 
 0.465
DYA
Ig-like domain-containing protein; Belongs to the MHC class II family.
   
   0.463
S100A12
Protein S100; Belongs to the S-100 family.
   
 
 0.430
PGLYRP1
Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.
   
  
 0.429
PRTN3
Proteinase 3; Belongs to the peptidase S1 family.
   
 
 0.424
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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