STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LY6DLymphocyte antigen 6 family member D. (128 aa)    
Predicted Functional Partners:
SLURP1
UPAR/Ly6 domain-containing protein.
   
  
 0.606
W5NUT3_SHEEP
Toxin_TOLIP domain-containing protein.
  
  
 0.589
TRIM29
Tripartite motif containing 29.
   
  
 0.539
KRTDAP
Keratinocyte differentiation associated protein.
   
  
 0.536
LRG1
Leucine rich alpha-2-glycoprotein 1.
      
 0.533
BPIFB2
BPI fold containing family B member 2.
      
 0.532
GNG11
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.518
KRT84
Keratin 84; Belongs to the intermediate filament family.
   
  
 0.488
A2ML1
Alpha-2-macroglobulin like 1.
      
 0.485
EFHD2
EF-hand domain family member D2.
      
 0.481
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.