STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (751 aa)    
Predicted Functional Partners:
DMAC2
Distal membrane arm assembly complex 2.
      
 0.710
AASS
Aminoadipate-semialdehyde synthase.
   
  
 0.697
YPEL4
Yippee like 4.
      
 0.692
MYBPHL
Myosin binding protein H like.
      
 0.655
ACBD3
Acyl-CoA binding domain containing 3.
      
 0.614
TPK1
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
      
 0.606
SLC37A4
Solute carrier family 37 member 4.
      
 0.587
MTX2
Metaxin 2.
      
 0.574
AASDH
Aminoadipate-semialdehyde dehydrogenase.
      
 0.537
KYNU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family.
      
 0.535
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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