STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLH3MutL homolog 3. (1485 aa)    
Predicted Functional Partners:
MLH1
MutL homolog 1.
    
0.990
MSH3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.975
MSH4
MutS homolog 4.
  
 0.953
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.915
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.912
W5P5E4_SHEEP
DNA_MISMATCH_REPAIR_2 domain-containing protein.
  
 0.892
HFM1
Helicase for meiosis 1.
    
 
 0.865
RNF212B
Ring finger protein 212B.
      
 0.856
PMS1
PMS1 homolog 1, mismatch repair system component.
    
0.790
VTA1
Vesicle trafficking 1.
    
   0.770
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.