FMOD protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FMOD

Fibromodulin. (403 aa)

Predicted Functional Partners:

TGFB1

0.955

TGFB3

0.930

TGFB2

0.930

BGN

0.851

TNMD

0.827

LUM

0.809

COMP

0.785

OGN

0.769

PRELP

0.738

SPARC

0.704

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGN	COMP	ENSOARP00000008210	ENSOARP00000011746	Biglycan; May be involved in collagen fiber assembly.	Cartilage oligomeric matrix protein.	0.707
BGN	FMOD	ENSOARP00000008210	ENSOARP00000001720	Biglycan; May be involved in collagen fiber assembly.	Fibromodulin.	0.851
BGN	LUM	ENSOARP00000008210	ENSOARP00000016879	Biglycan; May be involved in collagen fiber assembly.	Lumican.	0.745
BGN	OGN	ENSOARP00000008210	ENSOARP00000008876	Biglycan; May be involved in collagen fiber assembly.	Osteoglycin.	0.727
BGN	PRELP	ENSOARP00000008210	ENSOARP00000001744	Biglycan; May be involved in collagen fiber assembly.	Proline and arginine rich end leucine rich repeat protein.	0.692
BGN	SPARC	ENSOARP00000008210	ENSOARP00000009697	Biglycan; May be involved in collagen fiber assembly.	Kazal-like domain-containing protein.	0.687
BGN	TGFB1	ENSOARP00000008210	ENSOARP00000008013	Biglycan; May be involved in collagen fiber assembly.	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]	0.861
BGN	TGFB3	ENSOARP00000008210	ENSOARP00000002156	Biglycan; May be involved in collagen fiber assembly.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.555
BGN	TNMD	ENSOARP00000008210	ENSOARP00000002468	Biglycan; May be involved in collagen fiber assembly.	Tenomodulin.	0.872
COMP	BGN	ENSOARP00000011746	ENSOARP00000008210	Cartilage oligomeric matrix protein.	Biglycan; May be involved in collagen fiber assembly.	0.707
COMP	FMOD	ENSOARP00000011746	ENSOARP00000001720	Cartilage oligomeric matrix protein.	Fibromodulin.	0.785
COMP	LUM	ENSOARP00000011746	ENSOARP00000016879	Cartilage oligomeric matrix protein.	Lumican.	0.542
COMP	PRELP	ENSOARP00000011746	ENSOARP00000001744	Cartilage oligomeric matrix protein.	Proline and arginine rich end leucine rich repeat protein.	0.508
COMP	TGFB1	ENSOARP00000011746	ENSOARP00000008013	Cartilage oligomeric matrix protein.	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]	0.601
COMP	TGFB3	ENSOARP00000011746	ENSOARP00000002156	Cartilage oligomeric matrix protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.464
COMP	TNMD	ENSOARP00000011746	ENSOARP00000002468	Cartilage oligomeric matrix protein.	Tenomodulin.	0.651
FMOD	BGN	ENSOARP00000001720	ENSOARP00000008210	Fibromodulin.	Biglycan; May be involved in collagen fiber assembly.	0.851
FMOD	COMP	ENSOARP00000001720	ENSOARP00000011746	Fibromodulin.	Cartilage oligomeric matrix protein.	0.785
FMOD	LUM	ENSOARP00000001720	ENSOARP00000016879	Fibromodulin.	Lumican.	0.809
FMOD	OGN	ENSOARP00000001720	ENSOARP00000008876	Fibromodulin.	Osteoglycin.	0.769