FMOD protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

FMOD

Fibromodulin. (403 aa)

Predicted Functional Partners:

FIBIN

0.993

TGFB1

0.951

TGFB2

0.950

TGFB3

0.949

TNMD

0.813

OGN

0.808

COMP

0.745

PRELP

0.741

BGN

0.738

LRR1

0.710

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGN	COMP	ENSOARP00000008210	ENSOARP00000011746	Biglycan; May be involved in collagen fiber assembly.	Cartilage oligomeric matrix protein.	0.685
BGN	FMOD	ENSOARP00000008210	ENSOARP00000001720	Biglycan; May be involved in collagen fiber assembly.	Fibromodulin.	0.738
BGN	LRR1	ENSOARP00000008210	ENSOARP00000022137	Biglycan; May be involved in collagen fiber assembly.	Leucine rich repeat protein 1.	0.789
BGN	OGN	ENSOARP00000008210	ENSOARP00000008876	Biglycan; May be involved in collagen fiber assembly.	Osteoglycin.	0.724
BGN	PRELP	ENSOARP00000008210	ENSOARP00000001744	Biglycan; May be involved in collagen fiber assembly.	Proline and arginine rich end leucine rich repeat protein.	0.670
BGN	TGFB1	ENSOARP00000008210	ENSOARP00000008013	Biglycan; May be involved in collagen fiber assembly.	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]	0.747
BGN	TGFB2	ENSOARP00000008210	ENSOARP00000012419	Biglycan; May be involved in collagen fiber assembly.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.625
BGN	TGFB3	ENSOARP00000008210	ENSOARP00000002156	Biglycan; May be involved in collagen fiber assembly.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.634
BGN	TNMD	ENSOARP00000008210	ENSOARP00000002468	Biglycan; May be involved in collagen fiber assembly.	Tenomodulin.	0.823
COMP	BGN	ENSOARP00000011746	ENSOARP00000008210	Cartilage oligomeric matrix protein.	Biglycan; May be involved in collagen fiber assembly.	0.685
COMP	FMOD	ENSOARP00000011746	ENSOARP00000001720	Cartilage oligomeric matrix protein.	Fibromodulin.	0.745
COMP	PRELP	ENSOARP00000011746	ENSOARP00000001744	Cartilage oligomeric matrix protein.	Proline and arginine rich end leucine rich repeat protein.	0.403
COMP	TGFB1	ENSOARP00000011746	ENSOARP00000008013	Cartilage oligomeric matrix protein.	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]	0.526
COMP	TGFB2	ENSOARP00000011746	ENSOARP00000012419	Cartilage oligomeric matrix protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.477
COMP	TGFB3	ENSOARP00000011746	ENSOARP00000002156	Cartilage oligomeric matrix protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.476
COMP	TNMD	ENSOARP00000011746	ENSOARP00000002468	Cartilage oligomeric matrix protein.	Tenomodulin.	0.634
FIBIN	FMOD	ENSOARP00000015568	ENSOARP00000001720	Fin bud initiation factor homolog.	Fibromodulin.	0.993
FMOD	BGN	ENSOARP00000001720	ENSOARP00000008210	Fibromodulin.	Biglycan; May be involved in collagen fiber assembly.	0.738
FMOD	COMP	ENSOARP00000001720	ENSOARP00000011746	Fibromodulin.	Cartilage oligomeric matrix protein.	0.745
FMOD	FIBIN	ENSOARP00000001720	ENSOARP00000015568	Fibromodulin.	Fin bud initiation factor homolog.	0.993