Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GLAAlpha-galactosidase. (439 aa)    
Predicted Functional Partners:
GLB1
Beta-galactosidase.
  
 
 0.991
PSAP
Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
   
 0.976
ARSA
Arylsulfatase A.
   
 
 0.962
GALC
Galactosylceramidase.
     
 0.960
HEXB
Beta-hexosaminidase.
  
 
 0.943
HEXA
Beta-hexosaminidase.
  
 
 0.943
LOC101112162
Beta-hexosaminidase.
  
 
 0.942
A4GALT
Alpha 1,4-galactosyltransferase (P blood group).
     
 0.928
GALM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
     
 0.923
A3GALT2
Uncharacterized protein.
     
 0.919
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.