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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLAAlpha-galactosidase. (439 aa)    
Predicted Functional Partners:
GLB1
Beta-galactosidase.
  
 
 0.978
GBA3
Glucosylceramidase beta 3 (gene/pseudogene); Belongs to the glycosyl hydrolase 1 family.
      
 0.958
HEXB
Beta-hexosaminidase.
  
 
 0.947
LOC101112162
Beta-hexosaminidase.
  
 
 0.947
GALC
Galactosylceramidase.
     
 0.945
ARSA
Arylsulfatase A.
   
 
 0.942
HEXA
Beta-hexosaminidase.
  
 
 0.938
GAA
Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.
     
 0.922
GALM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
     
 0.922
NEU1
Neuraminidase 1.
     
 0.914
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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