STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC183Coiled-coil domain containing 183. (538 aa)    
Predicted Functional Partners:
USP46
Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family.
      
 0.840
GPR151
G protein-coupled receptor 151.
      
 0.826
KCNS2
Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family.
      
 0.758
STK32B
Serine/threonine kinase 32B; Belongs to the protein kinase superfamily.
      
 0.734
TENM4
Uncharacterized protein.
      
 0.724
TMEM51
Transmembrane protein 51.
      
 0.709
SCN11A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.654
LINGO1
Leucine rich repeat and Ig domain containing 1.
      
 0.654
CTNNA3
Catenin alpha 3.
      
 0.586
TMPO
LEM domain-containing protein.
    
 
 0.586
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.