Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LTV1LTV1 ribosome biogenesis factor. (474 aa)    
Predicted Functional Partners:
NOB1
RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.
   
 0.999
BYSL
Bystin like.
   
 0.998
TSR1
TSR1 ribosome maturation factor.
   
 0.998
RIOK1
Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
   
 0.995
RIOK2
RIO kinase 2.
   
 0.994
RPS3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
   
 0.979
NOP14
NOP14 nucleolar protein.
   
 0.968
BUD23
BUD23 rRNA methyltransferase and ribosome maturation factor.
   
 0.966
KRR1
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
 
 0.965
DIMT1
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
   
 
 0.961
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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