STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMACHCMetabolism of cobalamin associated C. (280 aa)    
Predicted Functional Partners:
MMADHC
Metabolism of cobalamin associated D.
    
 0.897
DGKE
Diacylglycerol kinase.
      
 0.893
KIAA0408
KIAA0408.
      
 0.853
MTR
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 0.825
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif 13.
      
 0.792
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
     
 0.766
C6orf58
Chromosome 6 open reading frame 58.
   
  
 0.741
MMUT
Methylmalonyl-CoA mutase.
      
 0.741
THBD
Thrombomodulin.
    
 
 0.738
C2
Uncharacterized protein; Belongs to the peptidase S1 family.
      
 0.668
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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