STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
ARL3ADP-ribosylation factor-like 3; Belongs to the small GTPase superfamily. Arf family. (182 aa)    
Predicted Functional Partners:
UNC119
Unc-119 lipid binding chaperone.
    
 0.989
PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
   
 0.989
RP2
Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
    
 0.981
UNC119B
Unc-119 lipid binding chaperone B.
   
 0.915
NPHP3
TPR_REGION domain-containing protein.
    
 0.878
ELMOD2
ELMO domain containing 2.
      
 0.854
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
    
 0.846
IFT20
Intraflagellar transport 20.
   
 0.840
CFAP36
ARL2_Bind_BART domain-containing protein.
   
 
 0.807
W5P3S5_SHEEP
ARL2_Bind_BART domain-containing protein.
   
 
 0.807
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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