STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A2ML1Alpha-2-macroglobulin like 1. (1461 aa)    
Predicted Functional Partners:
HSPD1
Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family.
      
 0.697
APOH
Apolipoprotein H.
   
 0.670
MAL2
Mal, T cell differentiation protein 2 (gene/pseudogene).
   
  
 0.654
CBX8
Chromobox 8.
    
 0.639
TMEM63C
Transmembrane protein 63C.
      
 0.614
SAMD4B
Sterile alpha motif domain containing 4B.
      
 0.613
SH3YL1
SH3 and SYLF domain containing 1.
   
  
 0.589
HPX
Hemopexin.
   
 0.588
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein.
      
 0.587
CBX2
Chromobox 2.
    
 0.585
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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